Piero Portincasa Selected Research

Gallstones (Gallstone)

1/2022	Overcoming Ductal Block: Emergency ERCP and Sphincterotomy Plus Common Bile Duct Stenting Improves Therapeutic Outcomes in Severe Gallstone Pancreatitis.
12/2020	Activation of Estrogen Receptor G Protein-Coupled Receptor 30 Enhances Cholesterol Cholelithogenesis in Female Mice.
11/2020	An Update on the Lithogenic Mechanisms of Cholecystokinin a Receptor (CCKAR), an Important Gallstone Gene for Lith13.
3/2020	Physical Activity Modulating Lipid Metabolism in Gallbladder Diseases.
1/2020	Recent Advances in the Critical Role of the Sterol Efflux Transporters ABCG5/G8 in Health and Disease.
3/2019	Gastrointestinal defects in gallstone and cholecystectomized patients.
2/2019	The physical presence of gallstone modulates ex vivo cholesterol crystallization pathways of human bile.
1/2019	The Role of Diet in the Pathogenesis of Cholesterol Gallstones.
1/2019	Critical Care Aspects of Gallstone Disease.
1/2019	Update on the Molecular Mechanisms Underlying the Effect of Cholecystokinin and Cholecystokinin-1 Receptor on the Formation of Cholesterol Gallstones.

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Piero Portincasa Research Topics

Disease

48	Gallstones (Gallstone) 01/2022 - 04/2002
33	Cholelithiasis 11/2022 - 07/2002
31	Non-alcoholic Fatty Liver Disease 03/2022 - 01/2006
25	Fatty Liver 01/2022 - 01/2006
16	Obesity 04/2022 - 08/2014
16	Inflammation (Inflammations) 01/2021 - 01/2006
16	Insulin Resistance 11/2020 - 10/2010
14	Metabolic Syndrome (Dysmetabolic Syndrome X) 11/2020 - 12/2006
13	Fibrosis (Cirrhosis) 07/2021 - 01/2006
11	Liver Diseases (Liver Disease) 07/2021 - 09/2006
10	Liver Cirrhosis (Hepatic Cirrhosis) 07/2021 - 01/2005
9	Metabolic Diseases (Metabolic Disease) 01/2020 - 06/2008
8	Hepatocellular Carcinoma (Hepatoma) 03/2022 - 06/2011
8	Neoplasms (Cancer) 03/2022 - 07/2004
7	Cholestasis 11/2022 - 02/2007
7	Alcoholic Fatty Liver 04/2022 - 08/2006
6	Abdominal Pain (Pain, Abdominal) 06/2022 - 07/2015
6	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 01/2021 - 06/2014
6	Infections 01/2021 - 06/2017
5	COVID-19 06/2022 - 01/2020
5	Mitochondrial Diseases (Mitochondrial Disease) 01/2022 - 10/2007
5	Body Weight (Weight, Body) 09/2019 - 05/2012
5	Atherosclerosis 02/2019 - 01/2013
4	Constipation 01/2021 - 07/2007
4	Overweight 02/2020 - 08/2006
4	Weight Loss (Weight Reduction) 09/2019 - 08/2014
4	Digestive System Diseases 01/2018 - 01/2012
3	Dysbiosis 06/2022 - 04/2019
3	Pancreatitis 01/2022 - 12/2014
3	Dyslipidemias (Dyslipidemia) 12/2020 - 01/2007
3	Cardiovascular Diseases (Cardiovascular Disease) 12/2020 - 01/2012
3	Type 2 Diabetes Mellitus (MODY) 09/2019 - 07/2011
3	AIDS-Related Complex (ARC) 02/2019 - 02/2010
3	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 05/2014 - 02/2007
3	Necrosis 03/2010 - 10/2002
2	Fructose Intolerance (Intolerance, Fructose) 06/2022 - 07/2015
2	Thyroid Diseases (Thyroid Disease) 09/2021 - 07/2004
2	Hypertrophy 01/2021 - 01/2019
2	Alcoholic Liver Diseases (Alcoholic Liver Disease) 01/2021 - 01/2015
2	Celiac Disease (Celiac Sprue) 11/2020 - 01/2019

Drug/Important Bio-Agent (IBA)

51	CholesterolIBA 11/2022 - 04/2002
24	LipidsIBA 03/2022 - 03/2003
17	Bile Acids and Salts (Bile Acids)IBA 03/2020 - 03/2003
12	Proteins (Proteins, Gene)FDA Link 03/2022 - 10/2005
10	Fatty Acids (Saturated Fatty Acids)IBA 01/2022 - 01/2012
9	Pharmaceutical PreparationsIBA 07/2021 - 10/2002
8	Ezetimibe (Zetia)FDA Link 01/2017 - 06/2008
7	Biomarkers (Surrogate Marker)IBA 03/2022 - 04/2002
7	LeptinIBA 01/2021 - 01/2013
7	EnzymesIBA 11/2020 - 05/2007
7	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 02/2019 - 01/2007
6	AdiponectinIBA 04/2022 - 01/2017
6	Triglycerides (Triacylglycerol)IBA 01/2021 - 10/2010
6	Ursodeoxycholic Acid (Urso)FDA LinkGeneric 12/2018 - 06/2010
6	AntioxidantsIBA 10/2010 - 01/2006
5	FructoseIBA 06/2022 - 07/2015
5	Estrogens (Estrogen)FDA Link 12/2020 - 11/2009
5	Silybin (Lagosa)IBA 01/2020 - 05/2012
5	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 02/2015 - 06/2010
4	Colchicine FDA LinkGeneric 02/2020 - 12/2013
4	Transaminases (Aminotransferases)IBA 02/2020 - 01/2006
4	Lipoproteins (Lipoprotein)IBA 01/2019 - 01/2007
4	AdipokinesIBA 01/2019 - 01/2007
4	Nitric Oxide (Nitrogen Monoxide)FDA Link 08/2018 - 08/2008
4	MucinsIBA 01/2018 - 01/2008
4	Therapeutic UsesIBA 11/2017 - 02/2015
3	Phospholipids (Phosphatides)FDA LinkGeneric 11/2022 - 01/2006
3	SugarsIBA 11/2021 - 01/2019
3	Environmental Pollutants (Pollutants, Environmental)IBA 09/2021 - 12/2014
3	Nonesterified Fatty Acids (NEFA)IBA 05/2021 - 01/2007
3	Reactive Oxygen Species (Oxygen Radicals)IBA 05/2021 - 10/2007
3	Estrogen ReceptorsIBA 12/2020 - 09/2015
3	CarbohydratesIBA 11/2020 - 10/2014
3	PalmitatesIBA 01/2020 - 07/2016
3	Choline (Choline Chloride)IBA 01/2020 - 10/2007
3	Oleic Acid (Oleate)IBA 01/2020 - 07/2016
3	C-Reactive ProteinIBA 01/2020 - 08/2016
3	Thiobarbituric Acid Reactive SubstancesIBA 01/2017 - 12/2006
3	CytokinesIBA 01/2017 - 03/2010
3	ThioredoxinsIBA 01/2013 - 10/2005
3	Hemoglobins (Hemoglobin)IBA 01/2006 - 05/2004
3	Ribavirin (Virazole)FDA LinkGeneric 01/2006 - 05/2004
2	IsotopesIBA 07/2021 - 08/2006
2	PrebioticsIBA 01/2021 - 11/2020
2	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 12/2020 - 09/2015
2	Oral ContraceptivesIBA 11/2020 - 12/2014
2	Insulin (Novolin)FDA Link 11/2020 - 01/2013
2	Antiviral Agents (Antivirals)IBA 07/2020 - 01/2006

Therapy/Procedure

33	Therapeutics 01/2021 - 05/2004
8	Cholecystectomy 11/2022 - 08/2014
6	Bariatric Surgery 01/2020 - 08/2014
4	Laparoscopic Cholecystectomy 01/2017 - 06/2010
4	Liver Transplantation 11/2013 - 01/2005
3	Length of Stay 01/2022 - 08/2011
3	Total Parenteral Nutrition 11/2020 - 12/2018
3	Ligation 05/2010 - 02/2007
2	Aftercare (After-Treatment) 06/2022 - 09/2017
2	Hormone Replacement Therapy (Therapy, Hormone Replacement) 03/2022 - 12/2014
2	Secondary Prevention 07/2021 - 07/2016
2	Mediterranean Diet 07/2021 - 02/2020